megatomi.com - An Overview

Swiftly acquire sections as thin or thick as your application necessitates, without stressing about shedding or distorting worthwhile tissue samples.

Megatome is really a vibrating microtome designed to part a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome allows higher-throughput tissue sectioning with uniform area profile, together with nominal tissue damage and knowledge reduction.

Antibodies might acquire weeks to diffuse by only a few millimeters of tissue, that has a steep labeling gradient from surface to Main.

Megatome is designed for accuracy: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and incorporates a one of a kind deflection Handle system.

SE uses a rotational electrical subject to disperse really electromobile molecules (like antibodies or surfactant micelles) through a porous sample without the need of damaging electrically charged constructions inside the tissue. This enables 2-4 day clearing of intact organs,

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Megatome is a novel microtome which allows for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimum tissue harm and knowledge decline.

It’s time to enhance your microtome to Megatome. With precise large-frequency slicing for an unmatched range of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for numerous purposes.

Thoroughly delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.

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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, preserving specimens for numerous rounds of processing.

Leverage the Apparent+ tissue clearing method, together with eFLASH and patented stochastic electrotransport systems, to speedily apparent and label total organs. Critical highlights and characteristics include:

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